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Climbing dioecious herb 6 m or more, usually densely branchedwith tendrils.
Leaves alternate, simple cm long, deeply lobed,sinuate with mucronate tips; inflorescence a raceme; female and male flowers yellow, peduncle shorter on female flower, bracts on male peduncle reniform to rounded-cordate; fruit cylindrical, narrowed at both ends, cm long, prominent tubercles on the ribs, orange when ripe containing pendulous seeds covered in a red pulp; seed oblong mm x mm and mm thick.
Use for furuncles and common cold is classified as REC, based on the significant traditional use documented in the TRAMIL surveys, toxicity studies and available published scientific information. For topical application, strict hygienic measures should be observed in order to avoid contamination or additional infection.
Proximate analysis of g of leaf The aqueous extract of the leaf, in vitrodid not cause any activity against Plasmodium falciparum The decoction of the leaf did not exhibit any antifungal activity against Epidermophyton floccosum, Microsporum canis, Trichophyton mentagrophytes var.
The aqueous extract from the dried leaf at various concentrations showed insecticidal activity against Blatella germanica but not against Oncopeltus fasciatus at variable concentrations The aqueous methanolic extract of the leaf was inactive against Bacillus subtilis, while the petroleum ether extract was inactive against Candida albicans The chloroform, ether and methanol extracts were also active, though with a comparatively lower intensity Chloroform, ether, water and methanol extracts of the fruit in were active against Pseudomonas aeruginosa, Salmonella typhi and Shigella dysenteriaewhile the petroleum ether extract was inactive The aqueous alcoholic extract 1: The lyophilized extract obtained from g of leaf, applied with sterile gauze patches on the shaved skin of 14 New Zealand albino rabbits kg and 16 white Hantley guinea pigs both male and femaleobserved 24 and 72 hours after administration and followed by histopathological analysis based on biopsy, produced a primary irritation ratio below 5 not irritant or allergenic.
The fruit extract, extracted with acetone and purified in order to concentrate the hypoglycemic active principle, on intraperitoneal administration to mice, revealed signs of kidney toxicity due to the increase of urinary nitrogen levels, without noxious effects on liver, heart or blood Among pregnant rabbits, it caused 10 deaths and 2 uterus hemorrhages It also caused the destruction of a large number of different types of cells, except for Sertoli cells and basal spermatogonia cells, and result in a decrease in the epididymides lumen and deferent vessels was observed 60 days after administration Seed constituents a-trichosanthin, aand b-momorcharin are claimed to have an abortifacient effectThere is no available information documenting the safety of medicinal use for children or for women during breast feeding.
Wash the aerial parts of the plant thoroughly and crush them. Apply 30 grams a handful of vegetal material on the affected area of skin 3 times a day. There is no available information establishing a means of preparation and dosage other than that referred to by traditional use.
Chem Pharm Bull 32 5: Indian J Pharmacy Symposium Medicinal Plants and Spices. Indian J Exp Biol Isolation and characterization of momordicosides A and B, glycosides of a pentahydroxy-cucurbitane triterpene. Chem Pharm Bull28 9: Ann Bot London J Ethnopharmacol 13 3: Identity of abortifacient and ribosome-inactivating protein.
Int J Peptide Protein Res 31 3: Isolation and characterization of minor seed glycosides, momordicosides C, D and E. Chem Pharm Bull29 6: Screening of 38 plant extracts for anticandidal activity.
J Biilogicos 33 3: Int J Pharmacol29 1: Undergraduate special project report. Indian J Physiol Pharmacol20 2: Indian J Physiol Pharmacol15 2: Indian J Exp Biol14 5: Indian J Med Res48 4: Pakistan J Med Res2: West Indian Med J20 1: Int J Fertil33 2: Annual herbaceous, trailing vine. Stem slightly woody, rounded or slightly 5-angled; tendrils coiling and branching; leaves simple, shallowly lobed, pubescent 20 x biologlcos cm, petiole cm long; flowers unisexual, solitary, petals yellowish-orange, up to 15 cm long; fruits dull in colour, globose, sometimes cylindrical or pyriform, at least 15cm long, often with rounded ridges.
For topical application, strict hygiene measures should be observed in order to avoid contamination or additional infection. Due to the health risks involved in hepatic disorders, an initial medical evaluation is recommended. The use of this resource can be considered complementary to medical treatment, unless it is contraindicated. The entire plant contains citric, fumaric, succinic, malic and p -hydroxybenzoic acids, vitamin C 10xylitol The leaf juice and aqueous extract 1: El extracto acuoso 1.
ICR CD-1grupos de 6 machos y 6 hembras. The carotenes contained in the fruit and in a higher amount in the flower 13 act aopsitos inducers of DNA repair mechanisms By intraperitoneal administration the following LD 50 values were obtained:. Pathological study showed massive peritoneal irritation and abundant deposits of fibrinoid substances.
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The juice and aqueous extract 1: In the Soviet Pharmacopoeia, an oily solution applied in compresses and in the form of emulsions is cited, for treating chronic skin ailments and burns There is no available information documenting the safety of medicinal use in children or in women during pregnancy or while breast feeding. Prepare a decoction or infusion with grams of flowers in mL 1 cup of water.
In the case of the decoction, boil for at least 10 minutes in a covered pot; for infusion, add boiling water to 5 grams of flower. Filter, cool down and drink 1 cup 3 times a quemaduars Wash injury with boiled water and soap. Apply the leaf juice in sufficient quantity to affected area. Cover injury with dressing or clean cloth and replace twice a day.
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J Food Sci Zhongguo Yao Li Xue Bao 1 2: Hierba trepadora de hasta 6 m, usualmente muy ramificada. Corola amarilla, segmentos obtusos o emarginados de 1. A los compuestos presentes en la semilla a-tricosantina, ay la b-momorcharina se les atribuye efecto abortivoZarcillos simples o ramificados. Flores unisexuales, axilares, solitarias; corola amarillo-anaranjada de hasta 15 cm.
El zumo de hoja y el extracto acuoso 1: Quemaudras zumo y el extracto acuoso 1: A la cucurbitina se le atribuye baja toxicidad para humano 25 y perro El fruto y la flor de Cucurbita moschata constituyen un alimento de consumo humano relativamente extendido.
Skip to main content. Venezuela, Bolivarian Republic of. According to published and other information: Do not take orally during pregnancy due to risk of abortion.
apositos biologicos en quemaduras pdf
Not for use during lactation or by children under 3 years old. Chemical constituents of Momordica charantia: TRAMIL Research The lyophilized extract obtained from g of leaf, applied with sterile gauze patches on the shaved skin of 14 New Zealand albino rabbits kg and 16 white Hantley guinea pigs both male and femaleobserved 24 and 72 hours after administration and followed by biologiccos analysis based on biopsy, produced a primary irritation ratio below 5 not irritant or allergenic.
Not for use during pregnancy, during lactation or by children under 3 years old. By intraperitoneal administration the following LD 50 values were obtained: Cucurbitin shows low toxicity in in human 25 and dog The fruit and the flower of Cucurbita moschata are widely used for human consumption.
For asthenia and weakness There is no available information establishing a means of preparation and dosage other than that referred to by traditional use. Para astenia y debilidad: